Allergy and Immunology

Prof. John B. Ziegler AM

Professor Ziegler joined Sydney Children’s Hospital (SCH) in 1976 and UNSW in 1977. He is a
senior staff specialist in the Department of Immunology and Infectious Diseases and the HIV
Service, SCH. He was head of these services from their inception until 2015. He is a Fellow of the
Royal Australasian College of Physicians (RACP) and of the American Academy of Allergy
Asthma and Immunology.

He graduated in Medicine from the University of Sydney in 1966, gained fellowship of the RACP
in 1974, was awarded MD, University of NSW (UNSW) in 1995 and the Graduate Diploma in
Higher Education at UNSW in 1998. He trained in Clinical Immunology at St Vincent’s Hospital
in Sydney and Children’s Hospital, Boston.

He was cofounder of the Australasian Society of HIV Medicine, its first secretary and served as

He chairs the Immunoglobulin Users Advisory Group for NSW Health. He is an expert advisor on
prescription medicines for the Therapeutic Goods Administration and assists in the assessment of
drug licensing applications. He is on the advisory editorial boards of Journal of Clinical
Immunology In Practice, Australian Prescriber and MIMS.

Major contributions in HIV include the first description of mother-to-infant transmission of HIV
during breast feeding and the definition of the risk of HIV via breast feeding during maternal
seroconversion. He helped in the setting up of surveillance mechanisms for perinatal exposure to
HIV in Australia and has published a description of patterns of perinatal exposure to HIV in
Australia. He and his team have worked to improve surveillance of perinatal exposure to HIV and
to better monitor treatment of HIV infected children.

His clinical interests include allergic diseases, arthritis and related disorders in children and immune

He established the collaboration which identified the genetic cause of the syndrome of veno-
occlusive disease with immune deficiency and has now adopted a genomic approach to solving
genetic questions in primary immunodeficiencies. Current research interests include genetics of
congenital immune deficiency disorders, and epidemiology and diagnosis and management of
severe food allergy in Australian children. He has compared the methods used in Holocaust denial
with those used in attempts to refute a relationship between HIV and AIDS. He has authored more
than 160 peer reviewed publications in the medical literature.

He married Mary Stein in 1969 and they have 3 children and 7 grandchildren. Being inept at
handling spherical objects of any size, for exercise he prefers to bicycle around Sydney with a few
friends. In 2009 he was awarded membership of the Order of Australia (AM).